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Biological samples for cases of sudden unexpected death in infancy (SUDI) included in the biobank “BioMIN” and number of samples available in the biological resource centre of Nantes University Hospital as of 31 December 2022
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Noncompartmental Pharmacokinetic Parameters for Ondansetron in Brain, Spinal Cord and <t> Cerebrospinal Fluid </t> Following Co-administration IV of Ondansetron (10 mg/kg) and Tariquidar (7.5 mg/kg)
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Noncompartmental Pharmacokinetic Parameters for Ondansetron in Brain, Spinal Cord and <t> Cerebrospinal Fluid </t> Following Co-administration IV of Ondansetron (10 mg/kg) and Tariquidar (7.5 mg/kg)
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Noncompartmental Pharmacokinetic Parameters for Ondansetron in Brain, Spinal Cord and <t> Cerebrospinal Fluid </t> Following Co-administration IV of Ondansetron (10 mg/kg) and Tariquidar (7.5 mg/kg)
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Noncompartmental Pharmacokinetic Parameters for Ondansetron in Brain, Spinal Cord and <t> Cerebrospinal Fluid </t> Following Co-administration IV of Ondansetron (10 mg/kg) and Tariquidar (7.5 mg/kg)
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(1) Monkeys were administered AβO three times per week for one month, and (2) twelve months after the final dose <t>cerebrospinal</t> fluid <t>(CSF)</t> was collected from the cisterna magna of both AβO-treated and vehicle-control individuals. (3) EVps were extracted from CSF using phosphoserine MagCapture beads, and (4) raw mass spectrometry scans were processed to identify proteins and peptides. (4) Data analysis included differential abundance testing at the protein level, followed by (5) gene ontology (GO) enrichment and disease ontology (DO) association to interpret functional and disease-related signatures.
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(1) Monkeys were administered AβO three times per week for one month, and (2) twelve months after the final dose <t>cerebrospinal</t> fluid <t>(CSF)</t> was collected from the cisterna magna of both AβO-treated and vehicle-control individuals. (3) EVps were extracted from CSF using phosphoserine MagCapture beads, and (4) raw mass spectrometry scans were processed to identify proteins and peptides. (4) Data analysis included differential abundance testing at the protein level, followed by (5) gene ontology (GO) enrichment and disease ontology (DO) association to interpret functional and disease-related signatures.
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(1) Monkeys were administered AβO three times per week for one month, and (2) twelve months after the final dose <t>cerebrospinal</t> fluid <t>(CSF)</t> was collected from the cisterna magna of both AβO-treated and vehicle-control individuals. (3) EVps were extracted from CSF using phosphoserine MagCapture beads, and (4) raw mass spectrometry scans were processed to identify proteins and peptides. (4) Data analysis included differential abundance testing at the protein level, followed by (5) gene ontology (GO) enrichment and disease ontology (DO) association to interpret functional and disease-related signatures.
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(1) Monkeys were administered AβO three times per week for one month, and (2) twelve months after the final dose <t>cerebrospinal</t> fluid <t>(CSF)</t> was collected from the cisterna magna of both AβO-treated and vehicle-control individuals. (3) EVps were extracted from CSF using phosphoserine MagCapture beads, and (4) raw mass spectrometry scans were processed to identify proteins and peptides. (4) Data analysis included differential abundance testing at the protein level, followed by (5) gene ontology (GO) enrichment and disease ontology (DO) association to interpret functional and disease-related signatures.
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(1) Monkeys were administered AβO three times per week for one month, and (2) twelve months after the final dose <t>cerebrospinal</t> fluid <t>(CSF)</t> was collected from the cisterna magna of both AβO-treated and vehicle-control individuals. (3) EVps were extracted from CSF using phosphoserine MagCapture beads, and (4) raw mass spectrometry scans were processed to identify proteins and peptides. (4) Data analysis included differential abundance testing at the protein level, followed by (5) gene ontology (GO) enrichment and disease ontology (DO) association to interpret functional and disease-related signatures.
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Image Search Results


Biological samples for cases of sudden unexpected death in infancy (SUDI) included in the biobank “BioMIN” and number of samples available in the biological resource centre of Nantes University Hospital as of 31 December 2022

Journal: European Journal of Pediatrics

Article Title: The French registry of sudden unexpected death in infancy (SUDI): a 7-year review of available data

doi: 10.1007/s00431-024-05727-9

Figure Lengend Snippet: Biological samples for cases of sudden unexpected death in infancy (SUDI) included in the biobank “BioMIN” and number of samples available in the biological resource centre of Nantes University Hospital as of 31 December 2022

Article Snippet: Cerebrospinal fluid , FluidX 0.5 ml/aliquot , − 80 °C , 134 , 170.

Techniques: Suspension, Clinical Proteomics

Noncompartmental Pharmacokinetic Parameters for Ondansetron in Brain, Spinal Cord and  Cerebrospinal Fluid  Following Co-administration IV of Ondansetron (10 mg/kg) and Tariquidar (7.5 mg/kg)

Journal: Pharmaceutical Research

Article Title: Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System

doi: 10.1007/s11095-024-03739-6

Figure Lengend Snippet: Noncompartmental Pharmacokinetic Parameters for Ondansetron in Brain, Spinal Cord and Cerebrospinal Fluid Following Co-administration IV of Ondansetron (10 mg/kg) and Tariquidar (7.5 mg/kg)

Article Snippet: Pooled rat plasma and cerebrospinal fluid (CSF) was purchased from BioIVT (Westbury, NY, USA).

Techniques:

(1) Monkeys were administered AβO three times per week for one month, and (2) twelve months after the final dose cerebrospinal fluid (CSF) was collected from the cisterna magna of both AβO-treated and vehicle-control individuals. (3) EVps were extracted from CSF using phosphoserine MagCapture beads, and (4) raw mass spectrometry scans were processed to identify proteins and peptides. (4) Data analysis included differential abundance testing at the protein level, followed by (5) gene ontology (GO) enrichment and disease ontology (DO) association to interpret functional and disease-related signatures.

Journal: bioRxiv

Article Title: African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer’s-like Activation

doi: 10.1101/2025.10.08.678256

Figure Lengend Snippet: (1) Monkeys were administered AβO three times per week for one month, and (2) twelve months after the final dose cerebrospinal fluid (CSF) was collected from the cisterna magna of both AβO-treated and vehicle-control individuals. (3) EVps were extracted from CSF using phosphoserine MagCapture beads, and (4) raw mass spectrometry scans were processed to identify proteins and peptides. (4) Data analysis included differential abundance testing at the protein level, followed by (5) gene ontology (GO) enrichment and disease ontology (DO) association to interpret functional and disease-related signatures.

Article Snippet: Biofluids such as cerebrospinal fluid (CSF) provide an alternative window into central nervous system processes, enabling repeated sampling and longitudinal monitoring of AD-related changes from the earliest stages.

Techniques: Control, Mass Spectrometry, Functional Assay

Bar plots display significantly enriched Disease Ontology (DO) terms (adjusted p-value < 0.05) for regulated core proteins in cerebrospinal fluid (CSF). Enrichment analyses were conducted separately for the top 20%, 30%, 40%, and 50% of (A-D) upregulated and (E-H) downregulated proteins. DO terms are ranked by adjusted p-value. The x-axis indicates the number of proteins associated with each enriched disease category.

Journal: bioRxiv

Article Title: African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer’s-like Activation

doi: 10.1101/2025.10.08.678256

Figure Lengend Snippet: Bar plots display significantly enriched Disease Ontology (DO) terms (adjusted p-value < 0.05) for regulated core proteins in cerebrospinal fluid (CSF). Enrichment analyses were conducted separately for the top 20%, 30%, 40%, and 50% of (A-D) upregulated and (E-H) downregulated proteins. DO terms are ranked by adjusted p-value. The x-axis indicates the number of proteins associated with each enriched disease category.

Article Snippet: Biofluids such as cerebrospinal fluid (CSF) provide an alternative window into central nervous system processes, enabling repeated sampling and longitudinal monitoring of AD-related changes from the earliest stages.

Techniques: